THE STUDIES OF CELLULAR IMMUNITY TO GYNECOLOGIC TUMORS WITH MACROPHAGE MIGRATION INHIBITION TEST

Evaluation of cellular immunity in patients with asbestosis and workers exposed to asbestos

Introduction: A large number of studies have proved a relationship between maligant mesothelioma and workers exposed to asbestos. The purpose of this study was to evaluate the degree of immunocompetence of the asbestos workers in comparison with non asbestos workers. Methods and materials: In this study 7 asbestotic patients, 73 workers exposed to asbestos and 59 controls from 2 Farsit fact...

The behavior of leprous lymphocytes and macrophages in the macrophage migration-inhibition test.

Cellular immunity and immunotherapy of brain tumors.

Factors influencing the host immune response to central nervous system (CNS) tumors are not yet well understood. This review will outline what is known about anti-tumor immune responses against CNS tumors and describe how advances in our knowledge of basic immunology may be applied to brain tumor immunotherapy. We will first focus on cellular immune system interactions involved in peripheral an...

Inhibition of macrophage migration by muramyl peptides.

In the capillary tube migration system a synthetic muramyl dipeptide (MDP; N-acetylmuramyl-L-alanyl-D-isoglutamine), a part of bacterial cell wall peptidoglycans, inhibited the migration of peritoneal exudate macrophages from normal guinea pigs or rats. The migration inhibition was also caused by some MDP-containing peptidoglycan fragments from cell walls of Lactobacillus plantarum and Staphylo...

Effect of phytohaemagglutinin in the leucocyte migration inhibition test as a measure of cell-mediated immunity.

Evaluation of responsiveness to phytohaemagglutinin (PHA) in the leucocyte-migration inhibition test has been extended to a greater number of patients and control subjects to explore the range of the test. The patients, mainly with sarcoidosis, were found to be less responsive than controls. The conditions of the test in terms of concentration of PHA, duration of culture, and serum concentratio...